8DMU

Crystal structure of macrodomain CG3568 from Drosophila melanogaster in complex with ADP-ribose

Summary for 8DMU

Entry DOI	10.2210/pdb8dmu/pdb
Descriptor	CG3568, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, NICKEL (II) ION, ... (6 entities in total)
Functional Keywords	macrodomain, adp-ribose, complex, glycohydrolase, hydrolase
Biological source	Drosophila melanogaster (fruit fly)
Total number of polymer chains	4
Total formula weight	223920.03
Authors	Zhang, Z.,Das, C. (deposition date: 2022-07-08, release date: 2023-07-12, Last modification date: 2024-07-24)
Primary citation	Zhang, Z.,Fu, J.,Rack, J.G.M.,Li, C.,Voorneveld, J.,Filippov, D.V.,Ahel, I.,Luo, Z.Q.,Das, C. Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nat Commun, 15:2452-2452, 2024 Cited by PubMed: 38503748 DOI: 10.1038/s41467-024-46649-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation