8DM0

Cryo-EM structure of SARS-CoV-2 D614G spike protein in complex with VH ab6 (focused refinement of NTD and VH ab6)

8DM0 の概要

• エントリーDOI: 10.2210/pdb8dm0/pdb
• EMDBエントリー: 27522
• 分子名称: Spike glycoprotein, VH ab6, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: sars-cov-2, glycoprotein, fusion protein, viral protein, viral protein-immune system complex, vh ab6, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 155702.30

構造登録者

Zhu, X.,Mannar, D.,Saville, J.W.,Srivastava, S.S.,Berezuk, A.M.,Zhou, S.,Tuttle, K.S.,Subramaniam, S. (登録日: 2022-07-08, 公開日: 2022-08-31)

• 主引用文献: Mannar, D.,Saville, J.W.,Sun, Z.,Zhu, X.,Marti, M.M.,Srivastava, S.S.,Berezuk, A.M.,Zhou, S.,Tuttle, K.S.,Sobolewski, M.D.,Kim, A.,Treat, B.R.,Da Silva Castanha, P.M.,Jacobs, J.L.,Barratt-Boyes, S.M.,Mellors, J.W.,Dimitrov, D.S.,Li, W.,Subramaniam, S.; SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.; Nat Commun, 13:4696-4696, 2022; PubMed: 35982054; DOI: 10.1038/s41467-022-32262-8

実験手法

ELECTRON MICROSCOPY (3.21 Å)