8DLS

Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8)

8DLS の概要

• エントリーDOI: 10.2210/pdb8dls/pdb
• EMDBエントリー: 27514
• 分子名称: Spike glycoprotein, Fab 4A8 heavy chain, Fab 4A8 light chain, ... (5 entities in total)
• 機能のキーワード: sars-cov-2, glycoprotein, fusion protein, viral protein, viral protein-immune system complex, gamma, p.1, 4a8
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 197496.92

構造登録者

Zhu, X.,Mannar, D.,Saville, J.W.,Srivastava, S.S.,Berezuk, A.M.,Zhou, S.,Tuttle, K.S.,Subramaniam, S. (登録日: 2022-07-08, 公開日: 2022-08-31)

• 主引用文献: Mannar, D.,Saville, J.W.,Sun, Z.,Zhu, X.,Marti, M.M.,Srivastava, S.S.,Berezuk, A.M.,Zhou, S.,Tuttle, K.S.,Sobolewski, M.D.,Kim, A.,Treat, B.R.,Da Silva Castanha, P.M.,Jacobs, J.L.,Barratt-Boyes, S.M.,Mellors, J.W.,Dimitrov, D.S.,Li, W.,Subramaniam, S.; SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.; Nat Commun, 13:4696-4696, 2022; PubMed: 35982054; DOI: 10.1038/s41467-022-32262-8

実験手法

ELECTRON MICROSCOPY (2.66 Å)