8DIW

Crystal structure of NavAb E96P as a basis for the human Nav1.7 Inherited Erythromelalgia S211P mutation

8DIW の概要

• エントリーDOI: 10.2210/pdb8diw/pdb
• 分子名称: Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE (3 entities in total)
• 機能のキーワード: voltage-gated sodium channel ion transport protein, membrane protein
• 由来する生物種: Aliarcobacter butzleri RM4018
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34381.75

構造登録者

Wisedchaisri, G.,Gamal El-Din, T.M.,Zheng, N.,Catterall, W.A. (登録日: 2022-06-29, 公開日: 2023-10-25, 最終更新日: 2023-11-15)

• 主引用文献: Wisedchaisri, G.,Gamal El-Din, T.M.,Powell, N.M.,Zheng, N.,Catterall, W.A.; Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.; J.Gen.Physiol., 155:-, 2023; PubMed: 37903281; DOI: 10.1085/jgp.202313450

実験手法

X-RAY DIFFRACTION (3.11 Å)