8DFA

type I-C Cascade bound to ssDNA target

Summary for 8DFA

Entry DOI	10.2210/pdb8dfa/pdb
EMDB information	27403
Descriptor	pre-crRNA processing endonuclease, CRISPR-associated protein, TM1801 family, CRISPR-associated protein, CT1133 family, ... (6 entities in total)
Functional Keywords	crispr, type i-c, cascade, ssdna target, dna binding protein, dna binding protein-dna-rna complex, dna binding protein/dna/rna
Biological source	Desulfovibrio vulgaris str. Hildenborough More
Total number of polymer chains	13
Total formula weight	368984.84
Authors	O'Brien, R.E.,Bravo, J.P.K.,Ramos, D.,Hibshman, G.N.,Wright, J.T.,Taylor, D.W. (deposition date: 2022-06-21, release date: 2023-02-22, Last modification date: 2024-06-12)
Primary citation	O'Brien, R.E.,Bravo, J.P.K.,Ramos, D.,Hibshman, G.N.,Wright, J.T.,Taylor, D.W. Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83:746-, 2023 Cited by PubMed: 36805026 DOI: 10.1016/j.molcel.2023.01.024 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation