8DEQ

Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein

Summary for 8DEQ

Entry DOI	10.2210/pdb8deq/pdb
EMDB information	27395
Descriptor	Spike glycoprotein E1, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ... (4 entities in total)
Functional Keywords	antibody alphavirus veev spike trimer glycoprotein, viral protein
Biological source	Venezuelan equine encephalitis virus More
Total number of polymer chains	8
Total formula weight	288197.69
Authors	Casner, R.G.,Verardi, R.,Roederer, M.,Shapiro, L. (deposition date: 2022-06-21, release date: 2023-06-28)
Primary citation	Sutton, M.S.,Pletnev, S.,Callahan, V.,Ko, S.,Tsybovsky, Y.,Bylund, T.,Casner, R.G.,Cerutti, G.,Gardner, C.L.,Guirguis, V.,Verardi, R.,Zhang, B.,Ambrozak, D.,Beddall, M.,Lei, H.,Yang, E.S.,Liu, T.,Henry, A.R.,Rawi, R.,Schon, A.,Schramm, C.A.,Shen, C.H.,Shi, W.,Stephens, T.,Yang, Y.,Florez, M.B.,Ledgerwood, J.E.,Burke, C.W.,Shapiro, L.,Fox, J.M.,Kwong, P.D.,Roederer, M. Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186:2672-2689.e25, 2023 Cited by PubMed: 37295404 DOI: 10.1016/j.cell.2023.05.019 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6 Å)

Structure validation