8DE8
Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPA mixed micelles
Summary for 8DE8
Entry DOI | 10.2210/pdb8de8/pdb |
EMDB information | 27387 |
Descriptor | Potassium channel, subfamily K, member 2a, (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, POTASSIUM ION (3 entities in total) |
Functional Keywords | ion channel, k2p, k2p2.1, trek1, trek-1, popa, membrane protein |
Biological source | Danio rerio (zebrafish) |
Total number of polymer chains | 2 |
Total formula weight | 73974.87 |
Authors | Schmidpeter, P.A.M.,Nimigean, C.M.,Riegelhaupt, P.M. (deposition date: 2022-06-20, release date: 2023-03-08) |
Primary citation | Schmidpeter, P.A.M.,Petroff 2nd, J.T.,Khajoueinejad, L.,Wague, A.,Frankfater, C.,Cheng, W.W.L.,Nimigean, C.M.,Riegelhaupt, P.M. Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1. Nat Commun, 14:1077-1077, 2023 Cited by PubMed: 36841877DOI: 10.1038/s41467-023-36765-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.82 Å) |
Structure validation
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