8DDV

Cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state4

Summary for 8DDV

• Entry DOI: 10.2210/pdb8ddv/pdb
• Related: 8DDQ 8DDR 8DDS 8DDT 8DDU
• EMDB information: 27343
• Descriptor: Transient receptor potential cation channel, subfamily M, member 3, Unidentified segment at the N-terminus of TRPM3, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... (6 entities in total)
• Functional Keywords: trpm3, ion channel, pip2, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 8
• Total formula weight: 644617.58

Authors

Zhao, C.,MacKinnon, R. (deposition date: 2022-06-19, release date: 2022-11-02, Last modification date: 2024-06-12)

• Primary citation: Zhao, C.,MacKinnon, R.; Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.; Neuron, 111:81-, 2023; PubMed: 36283409; DOI: 10.1016/j.neuron.2022.10.002

Experimental method

ELECTRON MICROSCOPY (3.2 Å)