8DDT

cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state2

Summary for 8DDT

• Entry DOI: 10.2210/pdb8ddt/pdb
• Related: 8DDQ 8DDR 8DDS
• EMDB information: 27341
• Descriptor: Transient receptor potential cation channel, subfamily M, member 3, Unidentified segment at the N-terminus of TRPM3, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... (6 entities in total)
• Functional Keywords: trpm3, ion channel, pip2, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 8
• Total formula weight: 645119.34

Authors

Zhao, C.,MacKinnon, R. (deposition date: 2022-06-18, release date: 2022-11-02, Last modification date: 2024-06-12)

• Primary citation: Zhao, C.,MacKinnon, R.; Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.; Neuron, 111:81-, 2023; PubMed: 36283409; DOI: 10.1016/j.neuron.2022.10.002

Experimental method

ELECTRON MICROSCOPY (3.1 Å)