8D7N

Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide

8D7N の概要

• エントリーDOI: 10.2210/pdb8d7n/pdb
• 分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide (3 entities in total)
• 機能のキーワード: transferase, circadian clock protein, period2, kinase, complex, transferase-circadian clock protein complex, transferase/circadian clock protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 72745.10

構造登録者

Philpott, J.M.,Freeberg, A.M.,Tripathi, S.M.,Partch, C.L. (登録日: 2022-06-07, 公開日: 2023-05-17, 最終更新日: 2023-10-25)

• 主引用文献: Philpott, J.M.,Freeberg, A.M.,Park, J.,Lee, K.,Ricci, C.G.,Hunt, S.R.,Narasimamurthy, R.,Segal, D.H.,Robles, R.,Cai, Y.,Tripathi, S.,McCammon, J.A.,Virshup, D.M.,Chiu, J.C.,Lee, C.,Partch, C.L.; PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.; Mol.Cell, 83:1677-1692.e8, 2023; PubMed: 37207626; DOI: 10.1016/j.molcel.2023.04.019

実験手法

X-RAY DIFFRACTION (1.66 Å)