8D6U
Rana catesbeiana saxiphilin:F-STX (soaked)
Summary for 8D6U
Entry DOI | 10.2210/pdb8d6u/pdb |
Descriptor | Saxiphilin, (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid (3 entities in total) |
Functional Keywords | saxiphilin, toxin resistance, saxitoxin, antitoxin |
Biological source | Lithobates catesbeianus (American bullfrog) |
Total number of polymer chains | 2 |
Total formula weight | 189970.13 |
Authors | Chen, Z.,Zakrzewska, S.,Minor, D.L. (deposition date: 2022-06-06, release date: 2022-11-02, Last modification date: 2023-10-18) |
Primary citation | Chen, Z.,Zakrzewska, S.,Hajare, H.S.,Alvarez-Buylla, A.,Abderemane-Ali, F.,Bogan, M.,Ramirez, D.,O'Connell, L.A.,Du Bois, J.,Minor Jr., D.L. Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119:e2210114119-e2210114119, 2022 Cited by PubMed: 36279441DOI: 10.1073/pnas.2210114119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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