8D6S
Rana catesbeiana saxiphilin mutant - Y558A:STX (co-crystal)
Summary for 8D6S
| Entry DOI | 10.2210/pdb8d6s/pdb |
| Descriptor | Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate (3 entities in total) |
| Functional Keywords | saxiphilin, toxin resistance, saxitoxin, antitoxin |
| Biological source | Lithobates catesbeianus (American bullfrog) |
| Total number of polymer chains | 2 |
| Total formula weight | 188320.40 |
| Authors | Chen, Z.,Zakrzewska, S.,Minor, D.L. (deposition date: 2022-06-06, release date: 2022-11-02, Last modification date: 2023-10-18) |
| Primary citation | Chen, Z.,Zakrzewska, S.,Hajare, H.S.,Alvarez-Buylla, A.,Abderemane-Ali, F.,Bogan, M.,Ramirez, D.,O'Connell, L.A.,Du Bois, J.,Minor Jr., D.L. Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119:e2210114119-e2210114119, 2022 Cited by PubMed: 36279441DOI: 10.1073/pnas.2210114119 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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