8D6S

Rana catesbeiana saxiphilin mutant - Y558A:STX (co-crystal)

8D6S の概要

• エントリーDOI: 10.2210/pdb8d6s/pdb
• 分子名称: Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate (3 entities in total)
• 機能のキーワード: saxiphilin, toxin resistance, saxitoxin, antitoxin
• 由来する生物種: Lithobates catesbeianus (American bullfrog)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 188320.40

構造登録者

Chen, Z.,Zakrzewska, S.,Minor, D.L. (登録日: 2022-06-06, 公開日: 2022-11-02, 最終更新日: 2023-10-18)

• 主引用文献: Chen, Z.,Zakrzewska, S.,Hajare, H.S.,Alvarez-Buylla, A.,Abderemane-Ali, F.,Bogan, M.,Ramirez, D.,O'Connell, L.A.,Du Bois, J.,Minor Jr., D.L.; Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.; Proc.Natl.Acad.Sci.USA, 119:e2210114119-e2210114119, 2022; PubMed: 36279441; DOI: 10.1073/pnas.2210114119

実験手法

X-RAY DIFFRACTION (2.6 Å)