8D4P

Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor Jun10-90-3-C1

Summary for 8D4P

• Entry DOI: 10.2210/pdb8d4p/pdb
• Descriptor: 3C-like proteinase, 2-chloro-N-[(1R)-2-{[2-(3-fluorophenyl)ethyl]amino}-2-oxo-1-(pyridin-3-yl)ethyl]-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl]acetamide (3 entities in total)
• Functional Keywords: inhibitor, protease, sars-cov-2, mpro, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34411.92

Authors

Butler, S.G.,Chen, Y.,Wang, J. (deposition date: 2022-06-02, release date: 2023-06-07, Last modification date: 2023-10-25)

• Primary citation: Butler, S.G.,Chen, Y.,Wang, J.; Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor Jun10-90-3-C1; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.04 Å)