8D3J
Crystal structure of human Apoptosis-Inducing Factor (AIF) complexed with 6-fluoro-2-methylquinolin-4-amine
Summary for 8D3J
| Entry DOI | 10.2210/pdb8d3j/pdb |
| Descriptor | Apoptosis-inducing factor 1, mitochondrial, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total) |
| Functional Keywords | oxidoreductase, mitochondrial import, oxidative phosphorylation, saxs |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 121407.00 |
| Authors | Brosey, C.A.,Tainer, J.A. (deposition date: 2022-06-01, release date: 2023-11-08, Last modification date: 2024-05-29) |
| Primary citation | Brosey, C.A.,Link, T.M.,Shen, R.,Moiani, D.,Burnett, K.,Hura, G.L.,Jones, D.E.,Tainer, J.A. Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nat.Chem.Biol., 2024 Cited by PubMed: 38671223DOI: 10.1038/s41589-024-01609-1 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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