8D2B
Crystal structure of theophylline aptamer in complex with TAL2
Summary for 8D2B
Entry DOI | 10.2210/pdb8d2b/pdb |
Descriptor | RNA (33-MER), 6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-ol, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | rna, aptamer, theophylline |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 22123.10 |
Authors | Menichelli, E.,Spraggon, G. (deposition date: 2022-05-28, release date: 2022-11-30, Last modification date: 2023-10-25) |
Primary citation | Menichelli, E.,Lam, B.J.,Wang, Y.,Wang, V.S.,Shaffer, J.,Tjhung, K.F.,Bursulaya, B.,Nguyen, T.N.,Vo, T.,Alper, P.B.,McAllister, C.S.,Jones, D.H.,Spraggon, G.,Michellys, P.Y.,Joslin, J.,Joyce, G.F.,Rogers, J. Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119:e2213117119-e2213117119, 2022 Cited by PubMed: 36413497DOI: 10.1073/pnas.2213117119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.44 Å) |
Structure validation
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