8D0Z

S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (focused refinement)

8D0Z の概要

• エントリーDOI: 10.2210/pdb8d0z/pdb
• EMDBエントリー: 27113
• 分子名称: Spike glycoprotein, S728-1157 Fab heavy chain variable region, S728-1157 Fab light chain variable region, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, cross-neutralizing antibody, neutralizing mab, variants of concern, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 450291.76

構造登録者

Ozorowski, G.,Torres, J.L.,Ward, A.B. (登録日: 2022-05-26, 公開日: 2023-03-22, 最終更新日: 2023-05-03)

• 主引用文献: Changrob, S.,Halfmann, P.J.,Liu, H.,Torres, J.L.,McGrath, J.J.C.,Ozorowski, G.,Li, L.,Wilbanks, G.D.,Kuroda, M.,Maemura, T.,Huang, M.,Zheng, N.Y.,Turner, H.L.,Erickson, S.A.,Fu, Y.,Yasuhara, A.,Singh, G.,Monahan, B.,Mauldin, J.,Srivastava, K.,Simon, V.,Krammer, F.,Sather, D.N.,Ward, A.B.,Wilson, I.A.,Kawaoka, Y.,Wilson, P.C.; Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants.; J.Clin.Invest., 133:-, 2023; PubMed: 36862518; DOI: 10.1172/JCI166844

実験手法

ELECTRON MICROSCOPY (3.7 Å)