8CZF
Human BAK in complex with the dF2 peptide
Summary for 8CZF
Entry DOI | 10.2210/pdb8czf/pdb |
Descriptor | Bcl-2 homologous antagonist/killer, DF2 peptide (3 entities in total) |
Functional Keywords | bak, activator, bcl-2 family, apoptosis |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 21613.30 |
Authors | Aguilar, F.,Keating, A.E. (deposition date: 2022-05-24, release date: 2023-01-11, Last modification date: 2023-10-25) |
Primary citation | Aguilar, F.,Yu, S.,Grant, R.A.,Swanson, S.,Ghose, D.,Su, B.G.,Sarosiek, K.A.,Keating, A.E. Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization. Structure, 31:265-281.e7, 2023 Cited by PubMed: 36706751DOI: 10.1016/j.str.2023.01.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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