8CWV

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing nanobody 2-31 and a human antibody CC12.1 Fab

8CWV の概要

• エントリーDOI: 10.2210/pdb8cwv/pdb
• 分子名称: Spike protein S1, VHH 2-31, CC12.1 Fab heavy chain, ... (5 entities in total)
• 機能のキーワード: cross-neutralizing antibody; nanobody; sars-cov-2; sarbecovirus; immune system; vhh; cc12.1, immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 87716.71

構造登録者

Liu, H.,Wilson, I.A. (登録日: 2022-05-19, 公開日: 2022-07-06, 最終更新日: 2023-10-18)

• 主引用文献: Xiang, Y.,Huang, W.,Liu, H.,Sang, Z.,Nambulli, S.,Tubiana, J.,Williams Jr., K.L.,Duprex, W.P.,Schneidman-Duhovny, D.,Wilson, I.A.,Taylor, D.J.,Shi, Y.; Superimmunity by pan-sarbecovirus nanobodies.; Cell Rep, 39:111004-111004, 2022; PubMed: 35738279; DOI: 10.1016/j.celrep.2022.111004

実験手法

X-RAY DIFFRACTION (2.51 Å)