8CTL
IscB and wRNA bound to Target DNA (locked state)
Summary for 8CTL
| Entry DOI | 10.2210/pdb8ctl/pdb |
| Related | 7UTN |
| EMDB information | 26994 |
| Descriptor | IscB, RNA (222-MER), DNA target strand, ... (4 entities in total) |
| Functional Keywords | crispr, iscb, hearo rna, omega rna, rna binding protein-rna-dna complex, rna binding protein/rna/dna |
| Biological source | synthetic construct More |
| Total number of polymer chains | 4 |
| Total formula weight | 165561.00 |
| Authors | Schuler, G.A.,Hu, C.,Ke, A. (deposition date: 2022-05-16, release date: 2022-06-15, Last modification date: 2024-02-14) |
| Primary citation | Schuler, G.,Hu, C.,Ke, A. Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9. Science, 376:1476-1481, 2022 Cited by PubMed: 35617371DOI: 10.1126/science.abq7220 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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