8CQA
Mycobacterium tuberculosis dihydrofolate reductase in complex with N-(4-(2,6-diamino-5-(cyclopropylethynyl)pyrimidin-4-yl)phenyl)acetamide
8CQA の概要
エントリーDOI | 10.2210/pdb8cqa/pdb |
分子名称 | Dihydrofolate reductase, ~{N}-[4-[2,6-bis(azanyl)-5-(2-cyclopropylethyl)pyrimidin-4-yl]phenyl]ethanamide, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total) |
機能のキーワード | dihydrofolate reductase mycobacterium tuberculosis, biosynthetic protein |
由来する生物種 | Mycobacterium tuberculosis |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 38132.94 |
構造登録者 | |
主引用文献 | Kirkman, T.J.,Dias, M.V.B.,Coyne, A.G. Expansion of a series of pyrimidine derivatives utilising fragment-based merging leads to increased affinity to Mycobacterium tuberculosis dihydrofolate reductase (unpublished currently) To Be Published, |
実験手法 |
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