8CN8
apo Pseudomonas aeruginosa FabF C164A mutant
Summary for 8CN8
Entry DOI | 10.2210/pdb8cn8/pdb |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2 (2 entities in total) |
Functional Keywords | inhibitor, transferase, fabf, complex, platencin, antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 4 |
Total formula weight | 175985.98 |
Authors | |
Primary citation | Georgiou, C.,Espeland, L.O.,Bukya, H.,Yadrykhinsky, V.,Haug, B.E.,Mainkar, P.,Brenk, R. New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023 Cited by DOI: 10.26434/chemrxiv-2023-cwk25PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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