8CLQ

Zearalenone lactonase of Streptomyces coelicoflavus mutant H286Y in complex with hydrolyzed zearalenone

8CLQ の概要

• エントリーDOI: 10.2210/pdb8clq/pdb
• 分子名称: Hydrolase, 2,4-dihydroxy-6-[(1E,10S)-10-hydroxy-6-oxoundec-1-en-1-yl]benzoic acid (3 entities in total)
• 機能のキーワード: zearalenone, mycotoxin, lactonase, carboxylesterase, esterase, hydrolase, biodegradation, streptomyces coelicoflavus
• 由来する生物種: Streptomyces coelicoflavus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 140802.21

構造登録者

Puehringer, D.,Mlynek, G. (登録日: 2023-02-17, 公開日: 2024-02-28, 最終更新日: 2024-03-20)

• 主引用文献: Fruhauf, S.,Puhringer, D.,Thamhesl, M.,Fajtl, P.,Kunz-Vekiru, E.,Hobartner-Gussl, A.,Schatzmayr, G.,Adam, G.,Damborsky, J.,Djinovic-Carugo, K.,Prokop, Z.,Moll, W.D.; Bacterial Lactonases ZenA with Noncanonical Structural Features Hydrolyze the Mycotoxin Zearalenone.; Acs Catalysis, 14:3392-3410, 2024; PubMed: 38449531; DOI: 10.1021/acscatal.4c00271

実験手法

X-RAY DIFFRACTION (1.53 Å)