8CH8

Crystal structure of the human PXR ligand-binding domain in complex with liranaftate

8CH8 の概要

• エントリーDOI: 10.2210/pdb8ch8/pdb
• 分子名称: Nuclear receptor subfamily 1 group I member 2, ~{O}-(5,6,7,8-tetrahydronaphthalen-2-yl) ~{N}-(6-methoxypyridin-2-yl)-~{N}-methyl-carbamothioate (3 entities in total)
• 機能のキーワード: nuclear receptor, pregnane x receptor, nuclear protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37075.89

構造登録者

Carivenc, C.,Derosa, Q.,Grimaldi, M.,Boulahtouf, A.,Balaguer, P.,Bourguet, W. (登録日: 2023-02-07, 公開日: 2024-02-21)

• 主引用文献: Carivenc, C.,Derosa, Q.,Grimaldi, M.,Boulahtouf, A.,Balaguer, P.,Bourguet, W.; Crystal structure of the human PXR ligand-binding domain in complex with liranaftate; To Be Published,

実験手法

X-RAY DIFFRACTION (2.15 Å)