8CFW

Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H05

Summary for 8CFW

• Entry DOI: 10.2210/pdb8cfw/pdb
• Descriptor: Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENINE, ... (8 entities in total)
• Functional Keywords: fragment screening, protein-ligand complex, drug discovery, sam-dependent methylation reactions, sahase, ahcy, hydrolase
• Biological source: Pseudomonas aeruginosa PAO1
• Total number of polymer chains: 4
• Total formula weight: 212704.12

Authors

Malecki, P.H.,Gawel, M.,Stepniewska, M.,Brzezinski, K. (deposition date: 2023-02-03, release date: 2024-02-21)

• Primary citation: Malecki, P.H.,Gawel, M.,Stepniewska, M.,Brzezinski, K.; Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry H05; To be published,

Experimental method

X-RAY DIFFRACTION (1.61 Å)