8CFM
Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment E08
Summary for 8CFM
Entry DOI | 10.2210/pdb8cfm/pdb |
Descriptor | Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENINE, ... (9 entities in total) |
Functional Keywords | fragment screening, protein-ligand complex, drug discovery, sam-dependent methylation reactions, sahase, ahcy, hydrolase |
Biological source | Pseudomonas aeruginosa PAO1 |
Total number of polymer chains | 4 |
Total formula weight | 212543.06 |
Authors | Malecki, P.H.,Gawel, M.,Stepniewska, M.,Brzezinski, K. (deposition date: 2023-02-03, release date: 2024-02-21) |
Primary citation | Malecki, P.H.,Gawel, M.,Stepniewska, M.,Brzezinski, K. Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry E08 To be published, |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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