8CCJ

Crystal structure of Mycobacterium smegmatis thioredoxin reductase in complex with NADPH

Summary for 8CCJ

• Entry DOI: 10.2210/pdb8ccj/pdb
• Descriptor: Thioredoxin reductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total)
• Functional Keywords: trxr, oxidoreductase
• Biological source: Mycolicibacterium smegmatis MC2 155
• Total number of polymer chains: 1
• Total formula weight: 36642.67

Authors

Fuesser, F.T.,Koch, O.,Kuemmel, D. (deposition date: 2023-01-27, release date: 2024-02-07)

• Primary citation: Fuesser, F.T.,Otten, P.,Kuemmel, D.,Junker, A.,Koch, O.; Fragment-based design of mycobacterial thioredoxin reductase inhibitors based on computational exploration of a huge virtual space; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)