8CB3

SARS-CoV Macro domain complexed with 3-(N-morpholino)propanesulfonic acid

Summary for 8CB3

Entry DOI	10.2210/pdb8cb3/pdb
Descriptor	Papain-like protease nsp3, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, ... (4 entities in total)
Functional Keywords	macro domain, nsp3, structural genomics, marseilles structural genomics program @ afmb, msgp, hydrolase
Biological source	Severe acute respiratory syndrome coronavirus
Total number of polymer chains	3
Total formula weight	56210.52
Authors	Morin, B.,Ferron, F.,Coutard, B.,Canard, B.,Marseilles Structural Genomics Program @ AFMB (MSGP) (deposition date: 2023-01-25, release date: 2024-02-07, Last modification date: 2025-02-26)
Primary citation	Ortega-Granda, O.,Morin, B.,Alvarez, K.,Feracci, M.,Coutard, B.,Canard, B.,Ferron, F.,Rabah, N. Derivatives of MOPS: Promising scaffolds for SARS Coronaviruses macro domain-targeted inhibition Febs J., 2025 Cited by DOI: 10.1111/febs.70039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.572 Å)

Structure validation