8CAR

Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL

8CAR の概要

• エントリーDOI: 10.2210/pdb8car/pdb
• 分子名称: Serine/threonine protein kinase, PHOSPHATE ION, NITRATE ION, ... (4 entities in total)
• 機能のキーワード: lanthipeptide, biosynthetic protein
• 由来する生物種: Thermomonospora curvata
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 93590.97

構造登録者

Martins, B.M.,Sigurdsson, A.,Duettmann, A.A.,Jasyk, M.,Dimos-Roehl, B.,Schoepf, F.,Gemander, M.,Knittel, C.H.,Schegotzki, R.,Schmid, B.,Kosol, S.,Pommerening, L.,Gonzalez-Viegas, M.,Seidel, M.,Huegelland, M.,Leimkuehler, S.,Dobbek, H.,Mainz, A.,Suessmuth, R. (登録日: 2023-01-24, 公開日: 2023-06-14, 最終更新日: 2023-11-15)

• 主引用文献: Sigurdsson, A.,Martins, B.M.,Duttmann, S.A.,Jasyk, M.,Dimos-Rohl, B.,Schopf, F.,Gemander, M.,Knittel, C.H.,Schnegotzki, R.,Schmid, B.,Kosol, S.,Pommerening, L.,Gonzales-Viegaz, M.,Seidel, M.,Hugelland, M.,Leimkuhler, S.,Dobbek, H.,Mainz, A.,Sussmuth, R.D.; Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.; Angew.Chem.Int.Ed.Engl., 62:e202302490-e202302490, 2023; PubMed: 37014271; DOI: 10.1002/anie.202302490

実験手法

X-RAY DIFFRACTION (2.68 Å)