8C7V

Phage display derived serum albumin binding knob domain engineered within a novel VH framework 3 bispecific antibody format

Summary for 8C7V

• Entry DOI: 10.2210/pdb8c7v/pdb
• Related: 8C7J
• Descriptor: Fab heavy chain, Fab light chain (3 entities in total)
• Functional Keywords: fab, immune system
• Biological source: Cricetulus griseus; More
• Total number of polymer chains: 6
• Total formula weight: 141992.58

Authors

Adams, R.,Macpherson, A. (deposition date: 2023-01-17, release date: 2023-06-07)

• Primary citation: Adams, R.,Joyce, C.,Kuravskiy, M.,Harrison, K.,Ahdash, Z.,Balmforth, M.,Chia, K.,Marceddu, C.,Coates, M.,Snowden, J.,Goursaud, E.,Menochet, K.,van den Elsen, J.,Payne, R.J.,Lawson, A.D.G.,Scott-Tucker, A.,Macpherson, A.; Serum albumin binding knob domains engineered within a V H framework III bispecific antibody format and as chimeric peptides.; Front Immunol, 14:1170357-1170357, 2023; PubMed: 37251411; DOI: 10.3389/fimmu.2023.1170357

Experimental method

X-RAY DIFFRACTION (1.61 Å)