8C6L

Human protein kinase CK2 alpha in complex with CK2-TN01

Summary for 8C6L

• Entry DOI: 10.2210/pdb8c6l/pdb
• Descriptor: Casein kinase II subunit alpha, 1,2-ETHANEDIOL, 5-azanyl-3-[(~{Z})-1-cyano-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]-3~{H}-pyrazole-4-carbonitrile, ... (5 entities in total)
• Functional Keywords: kinase domain, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40785.35

Authors

Dalle Vedove, A.,Cazzanelli, G.,Lolli, G. (deposition date: 2023-01-12, release date: 2024-04-24)

• Primary citation: Cazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Aiello, G.,Ruzzene, M.,Tiberi, L.,Fava, L.,Quattrone, A.,Lolli, G.; Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma; to be published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)