8C35

Dark state 2.1 Angstrom crystal structure of H132A variant of cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH

Summary for 8C35

• Entry DOI: 10.2210/pdb8c35/pdb
• Descriptor: Probable transcriptional regulator, COBALAMIN, 5'-DEOXYADENOSINE, ... (4 entities in total)
• Functional Keywords: carh, cobalamin, light-activated, transcription regulator, transcription
• Biological source: Thermus thermophilus HB27
• Total number of polymer chains: 4
• Total formula weight: 99097.31

Authors

Poddar, H.,Leys, D. (deposition date: 2022-12-23, release date: 2023-08-16, Last modification date: 2023-08-30)

• Primary citation: Poddar, H.,Rios-Santacruz, R.,Heyes, D.J.,Shanmugam, M.,Brookfield, A.,Johannissen, L.O.,Levy, C.W.,Jeffreys, L.N.,Zhang, S.,Sakuma, M.,Colletier, J.P.,Hay, S.,Schiro, G.,Weik, M.,Scrutton, N.S.,Leys, D.; Redox driven B 12 -ligand switch drives CarH photoresponse.; Nat Commun, 14:5082-5082, 2023; PubMed: 37604813; DOI: 10.1038/s41467-023-40817-6

Experimental method

X-RAY DIFFRACTION (2.1 Å)