8C2G
14-3-3 sigma with Pin1 binding site pS72 and covalently bound CV1040
Summary for 8C2G
Entry DOI | 10.2210/pdb8c2g/pdb |
Descriptor | 14-3-3 protein sigma, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, 2-iodanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, ... (5 entities in total) |
Functional Keywords | 14-3-3 sigma, pin1, covalent, stabilizer, peptide binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 29177.08 |
Authors | Verhoef, C.J.,Cossar, P. (deposition date: 2022-12-22, release date: 2023-06-14, Last modification date: 2023-07-05) |
Primary citation | Verhoef, C.J.A.,Kay, D.F.,van Dijck, L.,Doveston, R.G.,Brunsveld, L.,Leney, A.C.,Cossar, P.J. Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry. Chem Sci, 14:6756-6762, 2023 Cited by PubMed: 37350830DOI: 10.1039/d3sc01732j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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