8C2G

14-3-3 sigma with Pin1 binding site pS72 and covalently bound CV1040

Summary for 8C2G

• Entry DOI: 10.2210/pdb8c2g/pdb
• Descriptor: 14-3-3 protein sigma, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, 2-iodanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, ... (5 entities in total)
• Functional Keywords: 14-3-3 sigma, pin1, covalent, stabilizer, peptide binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 29177.08

Authors

Verhoef, C.J.,Cossar, P. (deposition date: 2022-12-22, release date: 2023-06-14, Last modification date: 2023-07-05)

• Primary citation: Verhoef, C.J.A.,Kay, D.F.,van Dijck, L.,Doveston, R.G.,Brunsveld, L.,Leney, A.C.,Cossar, P.J.; Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry.; Chem Sci, 14:6756-6762, 2023; PubMed: 37350830; DOI: 10.1039/d3sc01732j

Experimental method

X-RAY DIFFRACTION (1.6 Å)