8C2F

Structure of 14-3-3 sigma delta C with electrophilic peptide 3MHR-5

8C2F の概要

• エントリーDOI: 10.2210/pdb8c2f/pdb
• 分子名称: 14-3-3 protein sigma, ARG-ALA-HIS-SEP-CYS-PRO-ALA-SER-LEU-GLN, ethyl 3-bromanyl-2-methyl-propanoate, ... (6 entities in total)
• 機能のキーワード: 14-3-3 sigma, 3mhr-5, covalent, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28019.82

構造登録者

van den Oetelaar, M.C.M.,Ottmann, C. (登録日: 2022-12-22, 公開日: 2023-11-01, 最終更新日: 2023-12-13)

• 主引用文献: Gabizon, R.,Tivon, B.,Reddi, R.N.,van den Oetelaar, M.C.M.,Amartely, H.,Cossar, P.J.,Ottmann, C.,London, N.; A simple method for developing lysine targeted covalent protein reagents.; Nat Commun, 14:7933-7933, 2023; PubMed: 38040731; DOI: 10.1038/s41467-023-42632-5

実験手法

X-RAY DIFFRACTION (2.3 Å)