8C2E

Structure of 14-3-3 sigma delta C with electrophilic peptide 4IEA-5

Summary for 8C2E

• Entry DOI: 10.2210/pdb8c2e/pdb
• Descriptor: 14-3-3 protein sigma, ARG-SER-ALA-SEP-CYS-PRO-SER-LEU, ethyl 3-bromanyl-2-methyl-propanoate, ... (6 entities in total)
• Functional Keywords: 14-3-3 sigma, 4iea-5, covalent, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 27769.55

Authors

van den Oetelaar, M.C.M.,Ottmann, C. (deposition date: 2022-12-22, release date: 2023-11-01, Last modification date: 2023-12-13)

• Primary citation: Gabizon, R.,Tivon, B.,Reddi, R.N.,van den Oetelaar, M.C.M.,Amartely, H.,Cossar, P.J.,Ottmann, C.,London, N.; A simple method for developing lysine targeted covalent protein reagents.; Nat Commun, 14:7933-7933, 2023; PubMed: 38040731; DOI: 10.1038/s41467-023-42632-5

Experimental method

X-RAY DIFFRACTION (2.2 Å)