8C2E
Structure of 14-3-3 sigma delta C with electrophilic peptide 4IEA-5
Summary for 8C2E
Entry DOI | 10.2210/pdb8c2e/pdb |
Descriptor | 14-3-3 protein sigma, ARG-SER-ALA-SEP-CYS-PRO-SER-LEU, ethyl 3-bromanyl-2-methyl-propanoate, ... (6 entities in total) |
Functional Keywords | 14-3-3 sigma, 4iea-5, covalent, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 27769.55 |
Authors | van den Oetelaar, M.C.M.,Ottmann, C. (deposition date: 2022-12-22, release date: 2023-11-01, Last modification date: 2023-12-13) |
Primary citation | Gabizon, R.,Tivon, B.,Reddi, R.N.,van den Oetelaar, M.C.M.,Amartely, H.,Cossar, P.J.,Ottmann, C.,London, N. A simple method for developing lysine targeted covalent protein reagents. Nat Commun, 14:7933-7933, 2023 Cited by PubMed: 38040731DOI: 10.1038/s41467-023-42632-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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