8C1V
SARS-CoV-2 S-trimer (3 RBDs up) bound to TriSb92, fitted into cryo-EM map
Summary for 8C1V
Entry DOI | 10.2210/pdb8c1v/pdb |
EMDB information | 16383 |
Descriptor | Spike glycoprotein, Sb92, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | sars-cov-2 spike, sherpabody, viral protein, coronavirus |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 6 |
Total formula weight | 404600.45 |
Authors | |
Primary citation | Makela, A.R.,Ugurlu, H.,Hannula, L.,Kant, R.,Salminen, P.,Fagerlund, R.,Maki, S.,Haveri, A.,Strandin, T.,Kareinen, L.,Hepojoki, J.,Kuivanen, S.,Levanov, L.,Pasternack, A.,Naves, R.A.,Ritvos, O.,Osterlund, P.,Sironen, T.,Vapalahti, O.,Kipar, A.,Huiskonen, J.T.,Rissanen, I.,Saksela, K. Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants. Nat Commun, 14:1637-1637, 2023 Cited by PubMed: 36964125DOI: 10.1038/s41467-023-37290-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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