8C0L

FC-THF stabilizer of 14-3-3 and ERalpha

Summary for 8C0L

Entry DOI	10.2210/pdb8c0l/pdb
Descriptor	14-3-3 protein sigma, ERalpha peptide, Fusicoccin A-THF, ... (4 entities in total)
Functional Keywords	14-3-3, stabilization, eralpha, fusicoccin, structural protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	27735.24
Authors	Visser, E.J.,Ottmann, C. (deposition date: 2022-12-17, release date: 2024-07-10)
Primary citation	Visser, E.J.,Donaldson Collier, M.,Siefert, J.,Konstantinidou, M.,Paul, S.,Cossar, P.,Miley, G.,Meijer, O.,Arkin, M.R.,Ottmann, C.,Zwart, W.,Brunsveld, L. Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a potential intervention strategy for endocrine resistance in breast cancer To Be Published,
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation