8BZJ

Human MST3 (STK24) kinase in complex with inhibitor MRLW5

Summary for 8BZJ

• Entry DOI: 10.2210/pdb8bzj/pdb
• Descriptor: Serine/threonine-protein kinase 24, 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: selective kinase inhibitors, structure-based drug design, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 70079.26

Authors

Balourdas, D.I.,Rak, M.,Tesch, R.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC) (deposition date: 2022-12-14, release date: 2023-01-18, Last modification date: 2023-05-24)

• Primary citation: Balourdas, D.I.,Rak, M.,Tesch, R.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC); Human MST3 (STK24) kinase in complex with inhibitor MRLW5; to be published,

Experimental method

X-RAY DIFFRACTION (2.52 Å)