8BWW
Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs
Summary for 8BWW
| Entry DOI | 10.2210/pdb8bww/pdb |
| NMR Information | BMRB: 34778 |
| Descriptor | Thrombin light chain (1 entity in total) |
| Functional Keywords | host defence peptide, cd14, bacterial lps, de novo protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 2287.85 |
| Authors | Diehl, C. (deposition date: 2022-12-07, release date: 2023-09-06, Last modification date: 2023-11-15) |
| Primary citation | Petruk, G.,Puthia, M.,Samsudin, F.,Petrlova, J.,Olm, F.,Mittendorfer, M.,Hyllen, S.,Edstrom, D.,Stromdahl, A.C.,Diehl, C.,Ekstrom, S.,Walse, B.,Kjellstrom, S.,Bond, P.J.,Lindstedt, S.,Schmidtchen, A. Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs. Nat Commun, 14:6097-6097, 2023 Cited by PubMed: 37773180DOI: 10.1038/s41467-023-41702-y PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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