8BWR
Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with prostaglandin E2)
Summary for 8BWR
Entry DOI | 10.2210/pdb8bwr/pdb |
Related | 8BJF 8BWO 8BWP 8BWQ |
EMDB information | 16088 16292 16293 16294 16295 |
Descriptor | ATP-binding cassette sub-family C member 4, (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid (2 entities in total) |
Functional Keywords | abc transporter, abcc4, mrp4, pge2 bound abc transporter, translocase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 150046.39 |
Authors | Raj, I.,Bloch, M.,Pape, T.H.,Taylor, N.M.I. (deposition date: 2022-12-07, release date: 2023-08-30, Last modification date: 2023-11-15) |
Primary citation | Bloch, M.,Raj, I.,Pape, T.,Taylor, N.M.I. Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4. Structure, 31:1407-1418.e6, 2023 Cited by PubMed: 37683641DOI: 10.1016/j.str.2023.08.014 PDB entries with the same primary citation |
Experimental method |
Structure validation
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