8BVT
Cryo-EM structure of rat SLC22A6 bound to probenecid
Summary for 8BVT
Entry DOI | 10.2210/pdb8bvt/pdb |
EMDB information | 16271 |
Descriptor | Solute carrier family 22 member 6, Synthetic nanobody (Sybody), 4-(dipropylsulfamoyl)benzoic acid (3 entities in total) |
Functional Keywords | membrane protein, transporter |
Biological source | Rattus norvegicus (Christmas Island rat) More |
Total number of polymer chains | 2 |
Total formula weight | 76918.74 |
Authors | Parker, J.L.,Kato, T.,Newstead, S. (deposition date: 2022-12-06, release date: 2023-07-19, Last modification date: 2023-11-22) |
Primary citation | Parker, J.L.,Kato, T.,Kuteyi, G.,Sitsel, O.,Newstead, S. Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. Nat.Struct.Mol.Biol., 30:1786-1793, 2023 Cited by PubMed: 37482561DOI: 10.1038/s41594-023-01039-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.94 Å) |
Structure validation
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