8BUZ

Structure of Adenylyl cyclase 8 bound to stimulatory G-protein, Ca2+/Calmodulin, Forskolin and MANT-GTP

8BUZ の概要

• エントリーDOI: 10.2210/pdb8buz/pdb
• EMDBエントリー: 16252
• 分子名称: Adenylate cyclase type 8, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, FORSKOLIN, ... (5 entities in total)
• 機能のキーワード: adenylyl cyclase, camp signaling, g proteins, calmodulin, membrane protein
• 由来する生物種: Bos taurus (cattle); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 188170.18

構造登録者

Khanppnavar, B.,Korkhov, V.M.,Mehta, V. (登録日: 2022-12-01, 公開日: 2023-12-13, 最終更新日: 2024-06-12)

• 主引用文献: Khanppnavar, B.,Schuster, D.,Lavriha, P.,Uliana, F.,Ozel, M.,Mehta, V.,Leitner, A.,Picotti, P.,Korkhov, V.M.; Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.; Embo Rep., 25:1513-1540, 2024; PubMed: 38351373; DOI: 10.1038/s44319-024-00076-y

実験手法

ELECTRON MICROSCOPY (3.5 Å)