8BTO
Helical structure of BcThsA in complex with 1''-3'gcADPR
Summary for 8BTO
Entry DOI | 10.2210/pdb8bto/pdb |
Related | 8BTN 8BTP |
EMDB information | 16233 |
Descriptor | NAD(+) hydrolase ThsA, (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total) |
Functional Keywords | thoeris, sir2 domain, slog domain, 3'cadpr, hydrolase |
Biological source | Bacillus cereus MSX-D12 |
Total number of polymer chains | 12 |
Total formula weight | 679469.65 |
Authors | Tamulaitiene, G.,Sasnauskas, G.,Sabonis, D. (deposition date: 2022-11-29, release date: 2024-02-21, Last modification date: 2024-04-03) |
Primary citation | Tamulaitiene, G.,Sabonis, D.,Sasnauskas, G.,Ruksenaite, A.,Silanskas, A.,Avraham, C.,Ofir, G.,Sorek, R.,Zaremba, M.,Siksnys, V. Activation of Thoeris antiviral system via SIR2 effector filament assembly. Nature, 627:431-436, 2024 Cited by PubMed: 38383786DOI: 10.1038/s41586-024-07092-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.96 Å) |
Structure validation
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