8BPL

Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate

Summary for 8BPL

Entry DOI	10.2210/pdb8bpl/pdb
Descriptor	Carbamoyl-phosphate synthase (glutamine-hydrolyzing), PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, GLYCEROL, ... (5 entities in total)
Functional Keywords	nucleotide metabolism, de novo pyrimidine synthesis, cad, cysteine, disulfide bridge, protein stability, crosslinking, succinate, multienzymatic protein, transferase
Biological source	Thermochaetoides thermophila
Total number of polymer chains	1
Total formula weight	36393.78
Authors	del Cano-Ochoa, F.,Ramon-Maiques, S. (deposition date: 2022-11-16, release date: 2023-02-01, Last modification date: 2024-02-07)
Primary citation	Del Cano-Ochoa, F.,Rubio-Del-Campo, A.,Ramon-Maiques, S. A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD. Molecules, 28:-, 2023 Cited by PubMed: 36677714 DOI: 10.3390/molecules28020660 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation