8BPL

Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate

8BPL の概要

• エントリーDOI: 10.2210/pdb8bpl/pdb
• 分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: nucleotide metabolism, de novo pyrimidine synthesis, cad, cysteine, disulfide bridge, protein stability, crosslinking, succinate, multienzymatic protein, transferase
• 由来する生物種: Thermochaetoides thermophila
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36393.78

構造登録者

del Cano-Ochoa, F.,Ramon-Maiques, S. (登録日: 2022-11-16, 公開日: 2023-02-01, 最終更新日: 2024-02-07)

• 主引用文献: Del Cano-Ochoa, F.,Rubio-Del-Campo, A.,Ramon-Maiques, S.; A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.; Molecules, 28:-, 2023; PubMed: 36677714; DOI: 10.3390/molecules28020660

実験手法

X-RAY DIFFRACTION (1.58 Å)