8BOV

X-ray structure of the adduct formed upon reaction of the five-coordinate Pt(II) complex, 1-Me,Me, with HEWL at pH 7.5

This is a non-PDB format compatible entry.

Summary for 8BOV

• Entry DOI: 10.2210/pdb8bov/pdb
• Descriptor: Lysozyme, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... (6 entities in total)
• Functional Keywords: platinum, five-coordinate, glucoconjugate, metallodrug, protein interaction, hydrolase
• Biological source: Gallus gallus (chicken)
• Total number of polymer chains: 1
• Total formula weight: 15373.27

Authors

Ferraro, G.,Tito, G.,Merlino, A. (deposition date: 2022-11-15, release date: 2023-02-22, Last modification date: 2024-02-07)

• Primary citation: Annunziata, A.,Imbimbo, P.,Cucciolito, M.E.,Ferraro, G.,Langellotti, V.,Marano, A.,Melchiorre, M.,Tito, G.,Trifuoggi, M.,Monti, D.M.,Merlino, A.,Ruffo, F.; Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents.; Int J Mol Sci, 24:-, 2023; PubMed: 36768690; DOI: 10.3390/ijms24032369

Experimental method

X-RAY DIFFRACTION (1.25 Å)