8BGV

Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain

Summary for 8BGV

• Entry DOI: 10.2210/pdb8bgv/pdb
• EMDB information: 16039
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: protein fibril, amyloid
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 7
• Total formula weight: 321439.10

Authors

Behr, T.S.,Ryskeldi-Falcon, B. (deposition date: 2022-10-28, release date: 2023-05-24, Last modification date: 2024-07-24)

• Primary citation: Fowler, S.L.,Behr, T.S.,Turkes, E.,Cauhy, P.M.,Foiani, M.S.,Schaler, A.,Crowley, G.,Bez, S.,Ficulle, E.,Tsefou, E.,O'Brien, D.P.,Fischer, R.,Geary, B.,Gaur, P.,Miller, C.,D'Acunzo, P.,Levy, E.,Duff, K.E.,Ryskeldi-Falcon, B.; Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.; Biorxiv, 2023; PubMed: 37163117; DOI: 10.1101/2023.04.30.537820

Experimental method

ELECTRON MICROSCOPY (3.27 Å)