8BFC

Binary structure of 14-3-3s and RND3 phosphopeptide

Summary for 8BFC

• Entry DOI: 10.2210/pdb8bfc/pdb
• Descriptor: 14-3-3 protein sigma, Rho-related GTP-binding protein RhoE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: 14-3-3, hub-protein, phophopeptide, peptide binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 28366.44

Authors

Somsen, B.A.,Ottmann, C. (deposition date: 2022-10-24, release date: 2023-03-29, Last modification date: 2024-02-07)

• Primary citation: Somsen, B.A.,Schellekens, R.J.C.,Verhoef, C.J.A.,Arkin, M.R.,Ottmann, C.,Cossar, P.J.,Brunsveld, L.; Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.; J.Am.Chem.Soc., 145:6741-6752, 2023; PubMed: 36926879; DOI: 10.1021/jacs.2c12781

Experimental method

X-RAY DIFFRACTION (1.4 Å)